A New scientific achievement at E-JUST: developing a titanium alloy to manufacture lifelong cardiac stents

Prof. Ahmed El-Gohary, President of Egypt-Japan University of Science and Technology (E-JUST) announced that the university Centre for Innovative Technology has registered a new patent for developing a life-long titanium alloy with an excellent mechanical and biological compatibility for the manufacture of balloon-stretched medical stents, which are used for the treatment of heart failure. The patent has been granted to Prof. Mohamed Abdel-Hady Gepreel, Department of Materials Science and Engineering, and Eng. Adam Otabel, M.A., Student, Department of Materials Science and Engineering.


Prof. Mohamed Gepreel explained that vascular stents transplantation is widely known as one of the most successful methods of treating vascular insufficiency and stiffness. He added that a new titanium alloy, consisting of biologically- compatible elements, has been developed containing Niobium, tantalum and molybdenum elements, which achieve all the mechanical properties of the balloon-expandable stents. The alloy has low yield stress, and high strain hardening along with a large plastic formation. One of the distinguishing features of the alloy is the big difference between the yield stress and the maximum stress of the alloy, which is critical for ease and accuracy of stent placement and avoidance of stent failure during placement. The hemolysis rate test and cytotoxicity test reveal that when the alloy comes into contact with the blood, it will not harm the red blood cells or cause hemolysis and will show safe toxicity levels when used as a living transplanted tissue. In addition, the low magnetic sensitivity shown by the alloy is critical for stents to ensure correct and safe MRI diagnosis after stents placement.